coenzyme a

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coenzyme a

A scientist adds coenzyme A to a test tube in a laboratory.

Definition
  1. Noun:
    • A coenzyme present in all living cells; essential to the metabolism of carbohydrates, fats, and some amino acids: Coenzyme A is a crucial molecule that acts as a helper for enzymes, facilitating numerous biochemical reactions involved in breaking down and building up nutrients for energy and cellular function.
Usage Examples
  • Noun:
    • Acetyl-CoA, a molecule formed by attaching an acetyl group to coenzyme A, is a central intermediate in metabolism.
    • The synthesis of fatty acids requires coenzyme A to activate the precursor molecules.
    • A deficiency in pantothenic acid, a vitamin used to synthesize coenzyme A, can impair energy production.
Advanced Usage
  • "Activated carrier": Coenzyme A often functions as an activated carrier of specific chemical groups (like acetyl or acyl groups) within metabolic pathways.
    • In the citric acid cycle, coenzyme A carries acetyl groups to be oxidized for energy.
Variants and Related Words
  • CoA (n): A common abbreviation for coenzyme A.
    • The reaction yields acetyl-CoA.
  • Acyl-CoA (n): A class of molecules formed when a fatty acid chain is attached to coenzyme A, crucial for fat metabolism.
    • Acyl-CoA synthetase is the enzyme that forms acyl-CoA.
Synonyms
  • Metabolic cofactor: A substance that assists in metabolic reactions.
  • Carrier molecule: A molecule that transports chemical groups during reactions.
Related Phrases
  • Coenzyme A synthesis: The biochemical pathway that produces coenzyme A from its components, including pantothenic acid (vitamin B5).
    • The study focused on the regulation of coenzyme A synthesis in the liver.
coenzyme a

A scientist adds coenzyme A to a test tube in a laboratory.

Noun
  1. a coenzyme present in all living cells; essential to metabolism of carbohydrates and fats and some amino acids

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