glutamic oxalacetic transaminase

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glutamic oxalacetic transaminase

A doctor reviews a patient's blood test results showing elevated glutamic oxalacetic transaminase levels.

Definition
  1. Noun:
    • An enzyme involved in transamination: Glutamic oxalacetic transaminase is a specific enzyme that catalyzes a transamination reaction, transferring an amino group between aspartate and alpha-ketoglutarate. It is also commonly known by the abbreviation GOT and is now more formally called aspartate transaminase (AST).
Usage Examples
  • Noun:
    • Elevated levels of glutamic oxalacetic transaminase in the blood can indicate liver damage.
    • The laboratory test measured the activity of glutamic oxalacetic transaminase.
Advanced Usage
  • Clinical Context: The term is primarily used in medical and biochemical contexts, especially in diagnosing and monitoring conditions like myocardial infarction or hepatitis.
    • The doctor ordered a test for serum glutamic oxalacetic transaminase to assess the patient's cardiac health.
Variants and Related Words
  • Aspartate transaminase (AST): The modern, more precise name for the same enzyme.
  • Serum glutamic-oxaloacetic transaminase (SGOT): The term used when referring to the enzyme's level measured in blood serum.
  • Transaminase: The general class of enzymes to which it belongs.
Synonyms
  • Aspartate aminotransferase: The systematic synonym.
  • AST: The common acronym.
  • GOT: The older acronym.
Related Phrases
  • SGOT test: A common blood test panel that includes measurement of this enzyme.
    • The SGOT test is part of a standard liver function panel.
glutamic oxalacetic transaminase

A doctor reviews a patient's blood test results showing elevated glutamic oxalacetic transaminase levels.

Noun
  1. an enzyme involved in transamination