megaloblastic anaemia

Thân thiện

A doctor examines a blood smear showing megaloblastic anaemia under a microscope.

Definition

1. Noun:
   • A type of anemia: Megaloblastic anaemia is a blood disorder characterized by the presence of many large, immature, and dysfunctional red blood cells (called megaloblasts) in the bone marrow. This condition is often associated with a deficiency in vitamin B12 or folate, which are essential for proper red blood cell formation.

Usage Examples

• Noun:
  • The patient's fatigue and weakness were diagnosed as symptoms of megaloblastic anaemia.
  • A blood test revealed megaloblastic anaemia caused by a severe vitamin B12 deficiency.

Advanced Usage

• Clinical Context: The term is primarily used in medical and clinical settings to describe a specific hematological diagnosis.
  • The hematologist specialized in treating cases of megaloblastic anaemia.

Variants and Related Words

• Megaloblastic anemia (noun): An alternative spelling, primarily used in American English.
• Megaloblast (noun): The large, immature red blood cell precursor that characterizes this condition.
• Pernicious anemia (noun): A specific, autoimmune form of megaloblastic anaemia caused by an inability to absorb vitamin B12.

Synonyms

• Macrocytic anemia: A broader term for anemias featuring enlarged red blood cells, which includes megaloblastic anaemia as a primary type.

Related Phrases

• Vitamin B12 deficiency anaemia: A common cause of megaloblastic anaemia.
• Folate deficiency anaemia: Another common cause of megaloblastic anaemia.

Học thuật

Noun

1. anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia

Từ đồng nghĩa

• megaloblastic anemia