x-linked recessive inheritance

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x-linked recessive inheritance

A genetic counselor explains x-linked recessive inheritance using a family pedigree chart.

Definition

Noun: - A hereditary pattern in which a recessive gene located on the X chromosome results in the manifestation of the characteristic in male offspring and a carrier state in female offspring. This pattern of inheritance is specific to genes found on the X chromosome. Males, having only one X chromosome, will express the trait if their single X carries the recessive allele. Females, having two X chromosomes, will typically only be carriers if they possess one recessive allele, as the dominant allele on their other X chromosome usually prevents expression of the recessive trait.

Usage

This term is used in the fields of genetics, biology, and medicine to describe a specific mode of genetic transmission. - Hemophilia A is a classic example of X-linked recessive inheritance. - Genetic counselors explained the principles of X-linked recessive inheritance to the family.

Advanced Usage
  • "to follow a pattern of X-linked recessive inheritance": Describes a trait or disorder that is passed down according to this genetic rule.
    • Color blindness often follows a pattern of X-linked recessive inheritance.
Variants and Related Words
  • X-linked (adj): Referring to a gene located on the X chromosome.
    • Duchenne muscular dystrophy is an X-linked disorder.
  • Sex-linked inheritance (n): A broader category of inheritance for genes located on sex chromosomes (X or Y).
  • Carrier (n): An individual, typically female in this context, who has one copy of a recessive allele and does not show the trait but can pass it to offspring.
Synonyms
  • X-linked recessive trait
  • Sex-linked recessive inheritance (Note: This is often used synonymously, though technically it is a broader term that could also refer to genes on the Y chromosome).
Related Phrases
  • Manifest in males: A common phrase describing the outcome of this inheritance pattern.
    • Due to X-linked recessive inheritance, the condition manifests in males.
  • Carrier female: A standard term for a female who carries one copy of the recessive allele.
    • The mother was identified as a carrier female for the trait.
x-linked recessive inheritance

A genetic counselor explains x-linked recessive inheritance using a family pedigree chart.

Noun
  1. hereditary pattern in which a recessive gene on the X chromosome results in the manifestation of characteristics in male offspring and a carrier state in female offspring