angiotensin-converting enzyme
Definition
Noun: * Angiotensin-converting enzyme (ACE): A proteolytic enzyme (a type of protein that breaks down other proteins) that is crucial in the renin-angiotensin system. Its primary function is to convert the inactive peptide angiotensin I into the potent vasoconstrictor angiotensin II.
Usage Examples
- Noun:
- The doctor explained that the medication works by inhibiting angiotensin-converting enzyme.
- High levels of angiotensin-converting enzyme in the blood can be a marker for certain diseases.
- The action of angiotensin-converting enzyme increases blood pressure.
Advanced Usage
- "ACE inhibitor": A common class of drugs used to treat hypertension and heart failure by blocking the action of angiotensin-converting enzyme.
- He was prescribed an ACE inhibitor to manage his high blood pressure.
Variants and Related Words
- ACE: A widely used acronym for angiotensin-converting enzyme.
- The test measures serum ACE levels.
- Kinase II: An older, alternative name for the same enzyme.
- Peptidyl-dipeptidase A: The more precise biochemical name for angiotensin-converting enzyme.
Synonyms
- Peptidyl-dipeptidase A (biochemical synonym)
- Kinase II (historical synonym)
Related Phrases
- ACE activity: Refers to the functional level or measurement of the enzyme's action.
- The lab report showed reduced ACE activity after starting the medication.
- ACE pathway: Refers to the biochemical pathway involving this enzyme.
- Drugs target the ACE pathway to achieve their therapeutic effect.
Noun
-
proteolytic enzyme that converts angiotensin I into angiotensin II
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