karyolysis

Thân thiện

The biologist observed karyolysis in the stained tissue sample.

Definition

1. Noun:
   • The disintegration and dissolution of a cell nucleus when a cell dies: Karyolysis is a specific biological process where the chromatin of a dying cell's nucleus undergoes dissolution, causing the nucleus to lose its structure and stainable characteristics. It is a form of nuclear degradation.

Usage Examples

• Noun:
  • The pathologist noted extensive karyolysis in the tissue sample, indicating widespread cell death.
  • Karyolysis is often observed in cells undergoing necrosis, a form of traumatic cell death.

Advanced Usage

• Scientific Context: The term is used almost exclusively in histology, pathology, and cell biology to describe a morphological change in dead or dying cells.
  • Under the microscope, the hallmark of this type of cell injury is pyknosis, karyorrhexis, and finally karyolysis.

Variants and Related Words

• Karyolytic (adj): Relating to or characterized by karyolysis.
  • The karyolytic process was complete within hours.

Synonyms

• Nuclear dissolution: A descriptive synonym for the process.
• Chromatin dissolution: Refers specifically to the breakdown of the nuclear chromatin.

Related Terms (Conceptual)

• Pyknosis: The irreversible condensation of chromatin in the nucleus of a dying cell, often a stage before karyolysis.
• Karyorrhexis: The destructive fragmentation of the nucleus of a dying cell, another stage often preceding karyolysis.
• Necrosis: A form of cell injury which results in the premature death of cells, frequently involving karyolysis.

Học thuật

Noun

1. disintegration and dissolution of a cell nucleus when a cell dies