mutagenesis

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mutagenesis

Scientists perform mutagenesis on bacterial cultures in a laboratory.

Definition

Noun: The occurrence or process that causes a genetic mutation. It refers to an event or the action of an agent that induces a change in the structure of genetic material (DNA or RNA).

Usage

"Mutagenesis" is a technical term used primarily in biology, genetics, and medicine. It describes the initiation or causation of a mutation, not the mutation itself. It is often used to discuss laboratory techniques, environmental factors, or disease mechanisms.

Examples
  • In a scientific context:
    • The researcher studied the mutagenesis caused by ultraviolet radiation.
    • Site-directed mutagenesis is a common laboratory technique for studying gene function.
  • Describing a process:
    • The chemical's role in carcinogenesis is linked to its mutagenesis in epithelial cells.
Advanced Usage
  • "Site-directed mutagenesis": A precise molecular biology method to introduce specific, pre-determined changes into a DNA sequence.
    • They used site-directed mutagenesis to create a mutant version of the protein.
  • "Insertional mutagenesis": A process where a piece of DNA is inserted into a genetic sequence, disrupting the function of a gene.
    • The retrovirus caused disease through insertional mutagenesis.
Variants and Related Words
  • Mutagen (n): A physical or chemical agent that causes mutagenesis (e.g., X-rays, certain chemicals).
  • Mutagenic (adj): Having the ability to cause mutagenesis.
    • The substance was found to be mutagenic in bacterial tests.
  • Mutant (n/adj): An organism or gene carrying a mutation; resulting from mutation.
Synonyms
  • Mutation induction: The process of causing mutations.
  • Genotoxic event: An event that damages genetic information (a broader term that often includes mutagenesis).
Related Phrases
  • "Mechanism of mutagenesis": The specific way in which an agent causes genetic change.
    • The paper explored the mechanism of mutagenesis for the new compound.
  • "Rate of mutagenesis": The frequency at which mutations are induced.
    • The rate of mutagenesis was higher in the exposed population.
mutagenesis

Scientists perform mutagenesis on bacterial cultures in a laboratory.

Noun
  1. an event capable of causing a mutation

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