pyocyanin

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pyocyanin

A scientist examines a petri dish containing pyocyanin.

Definition

Noun: 1. A blue crystalline pigment with antibiotic properties: Pyocyanin is a blue-green phenazine compound produced by certain bacteria, notably Pseudomonas aeruginosa. It functions as a virulence factor and has antimicrobial activity against some other microorganisms. It is characteristically found in infected wounds, giving pus a greenish color.

Usage Examples
  • The laboratory confirmed the presence of in the culture, identifying the infection as .
  • The characteristic blue-green color of the wound drainage was due to .
  • Researchers are studying the antibiotic mechanisms of .
Advanced Usage
  • As a biological marker: In clinical microbiology, the production of pyocyanin is a key diagnostic feature for identifying .
    • The isolate's ability to produce pyocyanin on cetrimide agar confirmed the diagnosis.
  • In research contexts: Pyocyanin is studied for its role in bacterial communication (quorum sensing), its toxicity to human cells, and its potential applications.
    • The study focused on how pyocyanin facilitates anaerobic survival of the bacteria.
Variants and Related Words
  • Pyocyanic (adjective): Relating to or characterized by pyocyanin.
    • The pyocyanic pigment is a hallmark of the infection.
  • Pyocyanogenic (adjective): Capable of producing pyocyanin.
    • Pyocyanogenic strains are of particular clinical concern.
Synonyms
  • Antibiotic pigment (descriptive synonym)
  • Phenazine pigment (chemical class synonym)
Notes on Different Meanings

The word "pyocyanin" has a highly specialized, single meaning in microbiology and medicine. It does not have common idiomatic or figurative uses. Its definition is strictly tied to the specific blue-green compound produced by Pseudomonas aeruginosa.

pyocyanin

A scientist examines a petri dish containing pyocyanin.

Noun
  1. a toxic blue crystalline antibiotic found in green pus