Definition

Noun: * Sertoli's cell: An elongated cell found in the seminiferous tubules of the testis. Its primary function is to support, nourish, and protect developing sperm cells (spermatids) during the process of spermatogenesis.

Usage

• Sertoli's cells are a crucial component of the male reproductive system.
• They form the blood-testis barrier, which creates a protected environment for sperm development.
• These cells are often discussed in the context of male fertility and reproductive biology.

Examples

• In a biological description: "Sertoli's cells provide structural and metabolic support to the germ cells within the seminiferous tubules."
• In a medical context: "Damage to Sertoli's cells can impair spermatogenesis and lead to infertility."
• In an educational setting: "The student identified the Sertoli's cell on the histological slide of the testis."

Advanced Usage

• "Sertoli cell-only syndrome": A medical condition characterized by the presence of Sertoli's cells in the seminiferous tubules but a complete absence of germ cells, leading to azoospermia (no sperm in semen).
  • Example: "The biopsy results were consistent with Sertoli cell-only syndrome."

Variants and Related Words

• Sertoli cell (alternative spelling, without the possessive 's'): This form is increasingly common in modern scientific literature.
  • Example: "The Sertoli cell secretes androgen-binding protein."
• Nurse cell: A descriptive synonym highlighting the supportive and nourishing role of Sertoli's cells.
• Sustentacular cell: A broader histological term for supporting cells; Sertoli's cells are the sustentacular cells of the seminiferous tubules.

Synonyms

• Nurse cell
• Sustentacular cell (of the testis)

Related Terms (Not Synonyms)

• Spermatogenesis: The process of sperm production, which occurs in close association with Sertoli's cells.
• Seminiferous tubule: The tightly coiled tubes within the testis where sperm are produced and where Sertoli's cells are located.
• Leydig cell: Another cell type in the testis, responsible for producing testosterone, which works in concert with Sertoli's cells.

Noun

1. elongated cells found in the seminiferous tubules of the testis; apparently they nourish the spermatids