DNA chip

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Definition

Noun: - A microchip that holds DNA probes that form half of the DNA double helix and can recognize DNA from samples being tested. It is a technology used to analyze gene expression or detect genetic variations by allowing many DNA sequences to be tested simultaneously on a single small surface.

Usage
  • The term "DNA chip" is used primarily in scientific, medical, and biotechnological contexts to refer to a specific tool for genetic analysis.
  • It functions as a singular, countable noun (e.g., , ).
Examples
  • The laboratory used a DNA chip to screen for mutations in the patient's genome.
  • Researchers analyzed the gene expression profiles using a custom DNA chip.
  • The development of the DNA chip has revolutionized genetic testing.
Advanced Usage
  • "To hybridize to a DNA chip": This describes the process where sample DNA binds to the complementary probes on the chip.
    • The fluorescently labeled sample was allowed to hybridize to the DNA chip overnight.
  • "DNA chip data": Refers to the information or results obtained from an experiment using this technology.
    • The analysis of the DNA chip data revealed new patterns of gene activity.
Variants and Related Words
  • Microarray (n): A more general term for a lab tool used to detect the expression of many genes at once. A DNA chip is a specific type of microarray.
    • Gene expression microarrays are commonly used in research.
  • Gene chip (n): A synonym often used interchangeably with "DNA chip."
    • The Affymetrix GeneChip® is a well-known commercial platform.
Synonyms
  • Gene chip: A chip designed for genetic analysis.
  • DNA microarray: A broader technical term for a high-throughput technology used to measure the expression levels of many genes simultaneously.
Related Phrases
  • "To run a sample on a DNA chip": To perform an analysis using this technology.
    • We will run the tumor sample on a DNA chip to identify potential biomarkers.
  • "DNA chip technology": Refers to the field or methodology involving these devices.
    • Advances in DNA chip technology have made personalized medicine more feasible.
Noun
  1. a microchip that holds DNA probes that form half of the DNA double helix and can recognize DNA from samples being tested

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