Lorfan
Noun: - A pharmaceutical drug: "Lorfan" is a trade name for levallorphan tartrate, a medication chemically related to morphine. Its primary medical use is as an opioid antagonist to counteract severe respiratory depression caused by morphine or other opioid overdose, while intentionally preserving the pain-relieving (analgesic) effects of the opioid.
- As a proper noun (trade name): "Lorfan" is typically used with an initial capital letter, as it is a proprietary brand name.
- The emergency kit contained Lorfan to reverse the opioid's dangerous side effects.
- Administration of Lorfan requires careful medical supervision.
- In medical/clinical contexts: The term is used specifically in pharmacology and emergency medicine to describe this particular antagonist agent.
- The protocol specifies using Lorfan when respiratory arrest is a greater risk than pain.
- Levallorphan (n): The generic, non-proprietary name for the drug marketed as Lorfan.
- Opioid antagonist (n): The class of drugs to which Lorfan (levallorphan) belongs.
- Naloxone (n): A more commonly used modern opioid antagonist with a similar but distinct profile.
- Antidote (for opioid-induced respiratory depression): A substance used to counteract poisoning.
- Respiratory stimulant (in this specific context): An agent that promotes breathing.
This word has a single, highly specialized meaning within medical and pharmacological contexts. It is not used in everyday language. Its defining characteristic is its selective action: it antagonizes (blocks) the life-threatening respiratory depression caused by opioids without reversing their analgesic (pain-killing) effect, which distinguishes it from some other antagonists.
- drug (trade name Lorfan) that is related to morphine but that counteracts the respiratory depression produced by morphine poisoning but without affecting its analgesic effects