antihemophilic factor
Definition
Noun: 1. A specific clotting protein in blood plasma: Antihemophilic factor is a coagulation factor, specifically Factor VIII, which is essential for normal blood clotting. Its absence or deficiency causes Hemophilia A, a hereditary bleeding disorder.
Usage
- Medical Context: The term is used almost exclusively in medical, clinical, and scientific contexts to refer to the protein itself or its therapeutic preparations.
- The patient's blood test showed a severe deficiency of antihemophilic factor.
- Treatment involves regular intravenous infusions of antihemophilic factor concentrate.
Advanced Usage
- Therapeutic Preparations: The term can refer to the medicinal product derived from human plasma or produced recombinantly, used to treat or prevent bleeding episodes in individuals with Hemophilia A.
- The new recombinant antihemophilic factor has a lower risk of transmitting blood-borne pathogens.
Variants and Related Words
- Factor VIII: The standard scientific and medical synonym for antihemophilic factor.
- Coagulation Factor VIII: A more formal variant.
- Hemofil: A former brand name for a specific antihemophilic factor product.
Synonyms
- Factor VIII
- Coagulation Factor VIII
- (Plasma-derived or recombinant) Factor VIII concentrate
Notes on Meaning
- Primary Meaning: The protein (Factor VIII) that acts as a cofactor in the blood coagulation cascade.
- Clinical Meaning: The therapeutic substance administered to correct the deficiency in Hemophilia A.
Noun
-
a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A
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