axenic

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axenic

An axenic culture of bacteria grows in a sealed petri dish.

Definition
  1. Adjective:
    • (In microbiology) Completely free from other living organisms: Used specifically to describe a culture of microorganisms that contains only a single, intended species, with no contaminants.
    • (In biology) Raised under sterile, germ-free conditions: Used to describe laboratory animals that have been delivered by cesarean section and reared in a completely sterile, isolated environment to ensure they have no associated microbiota.
Usage Examples
  • Adjective (Microbiology context):

    • The researcher maintained an axenic culture of the bacteria for the purity of the experiment.
    • Achieving an axenic algal culture is challenging but essential for certain physiological studies.
  • Adjective (Experimental biology context):

    • The mice used in the study were axenic, allowing scientists to study the effects of specific introduced bacteria.
    • Rearing axenic animals requires specialized isolator technology.
Advanced Usage
  • "Axenic cultivation": The process of growing a single species in isolation from all others.

    • Axenic cultivation is a fundamental technique in microbiology.
  • "Axenic state": The condition of being free from foreign organisms.

    • The larvae were kept in an axenic state until the introduction of the test microbe.
Variants and Related Words
  • Aseptic (adj): Free from pathogenic microorganisms. (Note: "Aseptic" often refers to techniques to prevent infection, while "axenic" describes a state of biological purity.)
  • Gnotobiotic (adj): Referring to organisms or conditions where all present microorganisms are known. (An axenic organism is a type of gnotobiotic organism.)
  • Germfree (adj): Synonym for "axenic," especially in the context of animals.
Synonyms
  • Germfree
  • Sterile (in a biological, contaminant-free sense)
  • Pure culture (as a noun phrase for the microbiology context)
Notes on Meaning
  • This is a highly specialized scientific term. Its first meaning is most common in microbiology labs, and its second meaning is standard in immunology, gastroenterology, and experimental animal science.
  • It is distinct from general terms like "clean" or "pure." "Axenic" has a precise technical definition requiring the complete absence of all other living organisms.
axenic

An axenic culture of bacteria grows in a sealed petri dish.

Adjective
  1. (used of cultures of microorganisms) completely free from other organisms
    • an axenic culture
  2. (of experimental animals) raised under sterile conditions
    • axenic conditions
    • germfree animals

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