botheration

Noun

• something or someone that causes trouble; a source of unhappiness
  • washing dishes was a nuisance before we got a dish washer
    
  • a bit of a bother
    
  • he's not a friend, he's an infliction
    

• the psychological state of being irritated or annoyed

Related words

• Synonyms: 
  annoyance , bother , pain , infliction , pain in the neck , pain in the ass , irritation , vexation