cellular inclusion

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cellular inclusion

A scientist observes a cellular inclusion through a microscope.

Definition

Noun: 1. A small, distinct structure or particle found inside a cell: A "cellular inclusion" is a general term for any small, non-living body or aggregate of material located within the cytoplasm of a cell. These are often products of the cell's metabolism or accumulated substances and are characteristic of certain physiological states or diseases.

Usage
  • The term "cellular inclusion" is used in cell biology and pathology to describe diverse intracellular structures that are not considered permanent, functional organelles like mitochondria or the nucleus.
  • It is a broad, descriptive category. In scientific writing, the specific type of inclusion (e.g., lipid droplet, pigment granule, viral inclusion body) is usually named.
Examples
  • Under the microscope, the pathologist observed cellular inclusions in the liver cells, indicating a storage disorder.
  • The presence of specific cellular inclusions can be a diagnostic feature for certain viral infections.
  • Researchers studied the protein aggregates that form cellular inclusions in neurodegenerative diseases.
Advanced Usage
  • Inclusion bodies: This is a common and more specific term often used interchangeably with "cellular inclusions," particularly when referring to aggregates of viruses or misfolded proteins within a cell.
    • The virus causes the formation of characteristic inclusion bodies in the host cell's nucleus.
Variants and Related Words
  • Inclusion body (n): A specific type of cellular inclusion, often used in virology and neurology.
  • Cytoplasmic inclusion (n): A synonym emphasizing the inclusion's location in the cell's cytoplasm.
Synonyms
  • Intracellular inclusion
  • Cytoplasmic body
  • Inclusion body
Notes on Different Meanings
  • In materials science, an "inclusion" refers to a foreign material trapped within a solid, such as in a metal or gemstone. The term "cellular inclusion" is specific to biology and refers to structures within biological cells.
cellular inclusion

A scientist observes a cellular inclusion through a microscope.

Noun
  1. any small intracellular body found within another (characteristic of certain diseases)
    • an inclusion in the cytoplasm of the cell

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