deglycerolise
Definition
- Verb (transitive):
- To remove a substance (typically a biological material like blood cells or semen) from a glycerol solution or mixture. This is a specific technical process, often involving centrifugation and washing, to prepare the substance for use after it has been stored frozen with glycerol as a cryoprotectant.
Usage
- This verb describes a precise laboratory or medical procedure. It is almost exclusively used in scientific, medical, or technical contexts.
- It is a transitive verb and requires a direct object (the substance being processed).
- The process is the reverse of "glycerolizing" or "deglycerolizing."
Examples
- "Before transfusion, the frozen red blood cells must be deglycerolised to remove the cryoprotectant."
- "The protocol requires us to deglycerolise the semen sample slowly to maintain cell viability."
- "Deglycerolising the tissue samples is a critical step before they can be analyzed."
Advanced Usage
- The term is often used in procedural descriptions and standard operating protocols (SOPs) in fields like cryobiology, transfusion medicine, and assisted reproductive technology.
Variants and Related Words
- Deglycerolize (verb): The preferred spelling in American English.
- Deglycerolization / Deglycerolisation (noun): The process or act of deglycerolising.
- Example: "The deglycerolization of the blood product was successful."
- Glycerolize / Glycerolise (verb): The opposite process; to add or treat with glycerol, typically for cryopreservation.
- Cryoprotectant (noun): A substance like glycerol used to protect biological tissue from freezing damage.
Synonyms
- Wash (out) (in this specific context): To remove glycerol by rinsing with solutions.
- Note: "Wash" is a much more general term. "Deglycerolise" specifies the removal of glycerol specifically.
- Reconstitute (in a broader sense): To restore a preserved substance to its original state, which may involve deglycerolisation.
Antonyms
- Glycerolise / Glycerolize: To add or mix with glycerol.
- Cryopreserve: To preserve by freezing, a process which typically involves glycerolisation.
Verb
-
remove from glycerol
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