demyelination

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Definition
  1. Noun:
    • Loss of the myelin sheath: A pathological process where the protective myelin covering of nerve fibers is damaged or destroyed, leading to impaired nerve function.
Usage
  • The term is used in medical and neurological contexts to describe a key feature of various diseases.
  • It is a non-count noun, typically used without an indefinite article ("a demyelination").
Examples
  • Noun:
    • Multiple sclerosis is characterized by demyelination in the central nervous system.
    • The MRI scan showed evidence of demyelination along the spinal cord.
    • Researchers are studying the mechanisms that trigger demyelination.
Advanced Usage
  • "Demyelination of [nerve structure]": Specifies the location of the myelin loss.
    • The patient suffered from demyelination of the optic nerve, affecting vision.
  • "Focal demyelination": Refers to myelin loss occurring in specific, isolated areas.
    • The biopsy revealed areas of focal demyelination.
Variants and Related Words
  • Demyelinate (verb): To remove or destroy the myelin sheath.
    • The virus can demyelinate nerve fibers.
  • Demyelinating (adjective): Describing a disease or process that causes myelin loss.
    • Guillain-Barré syndrome is a demyelinating disorder of the peripheral nerves.
  • Myelin (noun): The fatty insulating sheath around nerve fibers.
  • Remyelination (noun): The process of repairing or regenerating the myelin sheath.
Synonyms
  • Myelin loss: The direct descriptive synonym.
  • Myelin breakdown: Emphasizes the degenerative aspect.
Related Phrases
  • Demyelinating disease: A category of illnesses where demyelination is the primary pathology.
    • Multiple sclerosis is the most common demyelinating disease.
  • Demyelinating neuropathy: Nerve damage specifically caused by loss of myelin.
    • The condition was diagnosed as a chronic demyelinating neuropathy.
Noun
  1. loss of the myelin covering of some nerve fibers resulting in their impaired function