deoxycytidine
- Noun:
- A nucleoside component of DNA: Deoxycytidine is a fundamental building block of deoxyribonucleic acid (DNA). It is composed of the nucleobase cytosine linked to the sugar deoxyribose.
- Noun:
- Deoxycytidine is one of the four nucleosides that make up DNA.
- The enzyme catalyzes the phosphorylation of deoxycytidine to form its corresponding nucleotide.
- Researchers studied the incorporation of a modified deoxycytidine into the DNA strand.
"Deoxycytidine monophosphate (dCMP)": The phosphorylated form of deoxycytidine, which is the actual nucleotide monomer incorporated into a DNA chain.
- DNA polymerase adds deoxycytidine monophosphate to the growing strand complementary to a guanine base on the template.
"Deoxycytidine kinase": An enzyme responsible for the phosphorylation of deoxycytidine, a key step in the nucleotide salvage pathway.
- The activity of deoxycytidine kinase is crucial for the activation of certain antiviral and anticancer drugs.
Cytidine (noun): The ribonucleoside counterpart, composed of cytosine and ribose, which is a component of RNA.
- Cytidine and deoxycytidine differ by a single oxygen atom on the sugar moiety.
Deoxycytidine triphosphate (dCTP) (noun): The triphosphate form, which is the direct substrate used by DNA polymerase during DNA synthesis.
- The replication fork requires a steady supply of dATP, dTTP, dGTP, and dCTP.
- dC (abbreviation): A common shorthand for deoxycytidine in biochemical contexts.
- 2'-Deoxycytidine (noun): The systematic chemical name, specifying the deoxy position on the ribose sugar.
Deoxycytidine analogue (noun phrase): A synthetic compound structurally similar to deoxycytidine, often used in antiviral or chemotherapy drugs.
- The drug is a deoxycytidine analogue that inhibits viral DNA polymerase.
Deoxycytidine deaminase (noun phrase): An enzyme that catalyzes the deamination of deoxycytidine to form deoxyuridine.
- The activity of deoxycytidine deaminase influences the intracellular pool of nucleotides.
-
a nucleoside component of DNA; composed of cytosine and deoxyribose
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