dna polymerase

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dna polymerase

A scientist observes DNA polymerase replicating a DNA strand in a test tube.

Definition
  1. Noun:
    • The enzyme responsible for DNA replication: DNA polymerase is a biological catalyst that synthesizes new strands of DNA by adding nucleotides complementary to an existing DNA template strand. It is essential for copying genetic material during cell division.
Usage Examples
  • Noun:
    • DNA polymerase is crucial for accurate genetic inheritance.
    • Scientists studied the structure of the DNA polymerase enzyme.
    • A mutation in the gene encoding DNA polymerase can lead to replication errors.
Advanced Usage
  • "DNA polymerase activity": Refers to the catalytic function of the enzyme in adding nucleotides.

    • The experiment measured the DNA polymerase activity in the sample.
  • "DNA polymerase proofreading": Describes the enzyme's ability to correct its own mistakes during replication.

    • The high fidelity of replication is due to DNA polymerase proofreading.
Variants and Related Words
  • Polymerase Chain Reaction (PCR): A laboratory technique that uses a heat-stable DNA polymerase to amplify specific DNA sequences.

    • PCR relies on a special type of DNA polymerase.
  • RNA polymerase: A related enzyme responsible for synthesizing RNA from a DNA template.

    • Transcription is carried out by RNA polymerase.
Synonyms
  • Replicase: A term sometimes used for enzymes involved in replication, though more common for viral RNA replication.
  • DNA synthetase: An older or less specific term for an enzyme that synthesizes DNA.
Related Phrases
  • "DNA polymerase III": The primary enzyme complex responsible for DNA replication in bacteria.

    • In E. coli, DNA polymerase III is the main replicative enzyme.
  • "Taq polymerase": A heat-stable DNA polymerase isolated from a thermophilic bacterium, widely used in PCR.

    • Taq polymerase is essential for the polymerase chain reaction.
dna polymerase

A scientist observes DNA polymerase replicating a DNA strand in a test tube.

Noun
  1. the enzyme responsible for DNA replication

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