ergonovine
Học thuậtThân thiện
Definition
Noun: 1. A specific medicinal alkaloid: A naturally occurring chemical compound (alkaloid) obtained from the fungus ergot. It is known for its ability to cause smooth muscle tissue, particularly that of the uterus, to contract. It is used medically after childbirth or abortion to control bleeding.
Usage Examples
- Noun:
- The obstetrician administered ergonovine to the patient to manage postpartum hemorrhage.
- Ergonovine is effective because it promotes strong contractions of the uterine muscle.
- A common side effect of ergonovine is an increase in blood pressure.
Advanced Usage
- Clinical Context: The term is primarily used in medical, pharmacological, and obstetric contexts. It is often discussed in relation to its mechanism of action (uterine contraction), indications (postpartum bleeding), and comparison to other ergot alkaloids like methylergonovine.
- In emergency protocols, ergonovine is listed as a second-line agent for uterine atony.
Variants and Related Words
- Ergotrate Maleate (n): A former trade name for ergonovine maleate, a common salt form of the alkaloid used in medication.
- Methylergonovine (n): A semi-synthetic derivative of ergonovine with similar uses but a slightly different pharmacological profile.
Synonyms
- Ergometrine (n): The British Approved Name (BAN) for the same compound. Ergonovine is the United States Adopted Name (USAN).
Notes on Meaning
- The core meaning of "ergonovine" is fixed as a specific pharmaceutical agent. It does not have idiomatic or phrasal verb uses. Its definition is centered on its origin (ergot), its chemical class (alkaloid), and its primary therapeutic action (uterine stimulant).
Noun
- an alkaloid derived from ergot (trade name Ergotrate Maleate) that is less toxic than ergot; induces muscular contraction of the uterus and is administered after childbirth or abortion