factor XI

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Definition

Noun: - A coagulation factor in blood plasma: Factor XI is a specific protein (clotting factor) that plays a crucial role in the intrinsic pathway of the blood coagulation cascade. Its deficiency can lead to a bleeding disorder.

Usage

Factor XI is a medical/scientific term used primarily in hematology, medicine, and biology contexts to discuss blood clotting processes and disorders. - It is typically used with verbs like activate, deficient in, requires, or involves. - It is often preceded by coagulation factor, clotting factor, or simply factor.

Examples
  • Noun:
    • The patient's prolonged bleeding time was due to a deficiency in factor XI.
    • Activation of factor XI is a key step in the amplification phase of coagulation.
    • The study focused on the genetic mutations affecting factor XI production.
Advanced Usage
  • "Factor XI deficiency": Also known as hemophilia C, this is a specific bleeding disorder.
    • Factor XI deficiency is typically milder than hemophilia A or B.
  • "Factor XIa": The activated form of the factor.
    • Factor XIa activates factor IX in the coagulation cascade.
Variants and Related Words
  • Plasma thromboplastin antecedent (PTA): An older, synonymous name for factor XI.
  • Coagulation factor XI: The full technical term.
  • F11: A common gene symbol for the gene encoding this factor.
Synonyms
  • Clotting factor XI: A direct synonym emphasizing its function.
  • PTA (Plasma thromboplastin antecedent): A historical synonym.
Related Terms (Not Phrasal Verbs/Idioms)

Given its technical nature, factor XI does not have phrasal verbs or idioms. It is part of specialized terminology. - Coagulation cascade: The series of steps in which factor XI participates. - Intrinsic pathway: The specific part of the coagulation cascade that factor XI is associated with. - Hemophilia C: The condition resulting from factor XI deficiency.

Noun
  1. coagulation factor whose deficiency results in a hemorrhagic tendency