Definition

Proper noun: * Fred Sanger: An English biochemist renowned for two major contributions to science. He determined the complete sequence of amino acids in the protein insulin, and he invented a groundbreaking method (the "dideoxy" or "Sanger method") for determining the precise order of nucleotides in DNA, enabling the reading of genetic sequences.

Usage Examples

• Proper noun:
  • Fred Sanger is one of only four individuals to have been awarded two Nobel Prizes.
  • The Sanger Institute in Cambridge is named in honor of Fred Sanger.
  • Modern genomics was made possible by the sequencing technique developed by Fred Sanger.

Advanced Usage

• "Sanger sequencing": This term refers specifically to the chain-termination DNA sequencing method invented by Fred Sanger. It is often used to distinguish this classical method from newer, next-generation sequencing technologies.
  • Although largely supplanted by high-throughput methods, Sanger sequencing is still the gold standard for validating genetic results.

Variants and Related Words

• Sanger method (n): Another name for Sanger sequencing.
• Dideoxy sequencing (n): The technical term for the Sanger method.

Synonyms

• There are no direct synonyms for a person's name. Related descriptive terms include: pioneering biochemist, Nobel laureate, sequencing pioneer.

Noun

1. English biochemist who determined the sequence of amino acids in insulin and who invented a technique to determine the genetic sequence of an organism (born in 1918)