glutamic oxaloacetic transaminase

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glutamic oxaloacetic transaminase

A scientist analyzes a blood sample for glutamic oxaloacetic transaminase levels.

Definition
  1. Noun:
    • An enzyme involved in transamination: Glutamic oxaloacetic transaminase (GOT) is a specific enzyme that catalyzes a chemical reaction called transamination, transferring an amino group between aspartate and alpha-ketoglutarate. It is also commonly known by its modern name, aspartate aminotransferase (AST).
Usage Examples
  • Noun:
    • Elevated levels of glutamic oxaloacetic transaminase in the blood can indicate liver or heart tissue damage.
    • The laboratory test measured serum glutamic oxaloacetic transaminase as part of the metabolic panel.
Advanced Usage
  • Clinical Context: In modern medical terminology, "aspartate aminotransferase (AST)" is the preferred term. "Glutamic oxaloacetic transaminase" is considered a legacy or historical name but is still understood.
    • The physician reviewed the patient's AST (formerly called glutamic oxaloacetic transaminase) levels.
Variants and Related Words
  • Aspartate aminotransferase (AST) (n): The modern, systematic name for the same enzyme.
  • Transaminase (n): A general class of enzymes to which GOT/AST belongs.
  • Enzyme (n): A protein that acts as a biological catalyst.
Synonyms
  • Aspartate aminotransferase (AST): The direct and primary synonym in current scientific and medical use.
  • Serum glutamic-oxaloacetic transaminase (SGOT): A synonym referring specifically to the enzyme when measured in blood serum.
Related Phrases
  • GOT/AST test: A common phrase referring to the blood test that measures this enzyme's activity.
    • The GOT/AST test is a standard part of a liver function panel.
glutamic oxaloacetic transaminase

A scientist analyzes a blood sample for glutamic oxaloacetic transaminase levels.

Noun
  1. an enzyme involved in transamination