immunoglobulin G

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Definition
  1. Noun:
    • A specific class of antibody: Immunoglobulin G (IgG) is one of the five primary types of antibodies (immunoglobulins) found in the blood and tissue fluids of vertebrates.
    • The primary antibody for bacterial defense: It is the most abundant antibody and plays the central role in the body's humoral immune response against bacterial infections.
Usage Examples
  • Noun:
    • The test showed high levels of immunoglobulin G, indicating a past infection.
    • Immunoglobulin G can cross the placenta, providing passive immunity to the fetus.
Advanced Usage

  • "IgG seropositivity": The state of having detectable IgG antibodies against a specific pathogen in the blood serum, often indicating prior exposure or vaccination.

    • IgG seropositivity for measles confirms the individual is immune.

  • "IgG subclass deficiency": A medical condition characterized by low levels of one or more of the four subclasses of Immunoglobulin G, leading to increased susceptibility to infections.

    • The child's recurrent pneumonia was linked to an IgG subclass deficiency.
Variants and Related Words

  • IgG (n): The common abbreviation for Immunoglobulin G.

    • The lab report listed the IgG level.

  • Immunoglobulin (n): The general term for a class of glycoprotein molecules produced by plasma cells that function as antibodies. Immunoglobulin G is a subtype.

    • There are five major types of immunoglobulins: IgA, IgD, IgE, IgG, and IgM.
Synonyms
  • Gamma globulin: A broad category of blood plasma proteins that includes antibodies; IgG is a major component.
  • Antibody: A protein produced by the immune system to neutralize pathogens. IgG is a specific type of antibody.
Related Phrases

  • IgG antibody titer: A measurement of the concentration of a specific IgG antibody in the blood.

    • A rising IgG antibody titer suggests an active or recent infection.

  • Intravenous Immunoglobulin (IVIG): A therapeutic preparation containing pooled IgG antibodies from donors, used to treat various immune deficiencies and autoimmune diseases.

    • The patient receives monthly IVIG infusions for their primary immunodeficiency.
Noun
  1. one of the five major classes of immunoglobulins; the main antibody defense against bacteria

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