inclusion body
Học thuậtThân thiện
Definition
- Noun:
- A small, distinct structure found inside a cell: An "inclusion body" is a microscopic, often abnormal, particle or aggregate that forms within the main body of a cell (the cytoplasm) or its nucleus. These bodies are not a normal part of the cell's structure and are typically associated with specific conditions, most notably certain viral infections and some genetic or degenerative diseases.
Examples of Usage
- Noun:
- The pathologist identified viral inclusion bodies in the infected tissue, confirming the diagnosis.
- Under the microscope, the characteristic inclusion bodies were clearly visible within the host cell's cytoplasm.
- The presence of these abnormal inclusion bodies is a hallmark of the disease.
Advanced Usage
- "Viral inclusion body": A specific type of inclusion body formed during the replication cycle of a virus inside an infected cell. They are often sites where viral components are assembled or stored.
- Negri bodies are a classic example of viral inclusion bodies found in rabies-infected neurons.
- "Cytoplasmic inclusion body" / "Nuclear inclusion body": These terms specify the location of the inclusion body within the cell.
- The inclusion bodies in this case were primarily cytoplasmic, rather than nuclear.
Variants and Related Words
- Inclusion (n): In cell biology, this is the more general term for any discrete structure inside a cell that is not an organelle. An "inclusion body" is a specific type of inclusion.
- Cytoplasmic inclusion (n): A synonym often used interchangeably with "inclusion body," emphasizing its location in the cell's cytoplasm.
Synonyms
- Cellular inclusion (n): A direct synonym.
- Inclusion (n): In the specific context of pathology and cell biology.
Related Phrases / Terms
- To contain inclusion bodies: A phrase describing a cell or tissue sample.
- The biopsy sample was found to contain numerous inclusion bodies.
- Inclusion body disease: A term for disorders characterized by the formation of these structures.
- Inclusion body myositis is a progressive muscle disease.
Noun
- any small intracellular body found within another (characteristic of certain diseases)
- an inclusion in the cytoplasm of the cell