indinavir

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indinavir

A doctor prescribes indinavir as part of an HIV treatment plan.

Definition

Noun: A synthetic antiviral drug belonging to the protease inhibitor class, used in the treatment of HIV infection. It works by blocking the activity of the HIV protease enzyme, which is necessary for the virus to replicate and produce infectious particles.

Usage

This word is used primarily in medical, pharmaceutical, and public health contexts. It refers specifically to the drug substance itself. - It is typically used as a non-count noun (e.g., "a dose of indinavir"). - It is often discussed in combination with other antiretroviral drugs as part of a treatment regimen.

Examples
  • Noun:
    • The doctor prescribed a combination therapy that included indinavir.
    • Early clinical trials demonstrated the efficacy of indinavir in reducing viral load.
    • A common side effect of indinavir is kidney stones.
Advanced Usage
  • "Indinavir sulfate": This is the sulfate salt form of the drug, which is the formulation used in medication.
    • The patient was administered 800 mg of indinavir sulfate every eight hours.
Variants and Related Words
  • Protease inhibitor (PI) (n): The broader class of drugs to which indinavir belongs.
    • Indinavir was one of the first protease inhibitors approved for use.
  • Antiretroviral (n/adj): A general term for drugs active against retroviruses like HIV.
    • Indinavir is a key component of many antiretroviral regimens.
Synonyms
  • Crixivan: This is the former brand name (tradename) for indinavir. While "Crixivan" is a synonym in terms of referring to the same drug, it is a proprietary name.
    • Crixivan (indinavir) is often used in combination with other medications.
Notes on Meaning

This word has one specific meaning: a pharmaceutical agent for treating HIV. It does not have idiomatic or figurative uses. It is not commonly used in phrasal verbs or idioms outside of very technical medical discussions (e.g., "indinavir resistance," "indinavir-based regimen").

indinavir

A doctor prescribes indinavir as part of an HIV treatment plan.

Noun
  1. a protease inhibitor (trade name Crixivan) used for treating HIV

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