isoniazid
Definition
Noun: - A synthetic antibacterial drug used primarily in the prevention and treatment of tuberculosis.
Usage
- Primary Medical Use: "Isoniazid" is a first-line medication prescribed as part of a combination therapy to treat active tuberculosis (TB) infection. It is also used alone to prevent TB in individuals who have been exposed.
- Example: The standard treatment for active tuberculosis includes a regimen of isoniazid and rifampin for several months.
- Example: After her positive skin test, she was placed on a nine-month course of isoniazid for latent TB infection.
Advanced Usage
- Pharmacological Context: The term is used in medical, pharmaceutical, and public health contexts. It is often abbreviated as INH in clinical notes and literature.
- Example: Patient tolerance to INH was good, with no signs of hepatotoxicity.
- Resistance: The concept of "isoniazid-resistant tuberculosis" is a significant concern in global health.
- Example: The emergence of isoniazid-resistant strains complicates treatment protocols.
Variants and Related Words
- INH: A common abbreviation for isoniazid.
- Isonicotinic acid hydrazide: The full chemical name for isoniazid.
Synonyms
- Antitubercular agent: A drug used to treat tuberculosis. (This is a category, not a direct synonym, but "isoniazid" is a specific member of this class.)
Notes
- Trade Name: A well-known trade name for isoniazid is Nydrazid. It is important to distinguish between the generic drug name (isoniazid) and its brand names.
- Example: The prescription was written for the generic isoniazid, not the brand-name Nydrazid.
Noun
-
antibacterial drug (trade name Nydrazid) used to treat tuberculosis
