kayser-fleischer ring
A doctor uses an ophthalmoscope to examine a patient's eye for a Kayser-Fleischer ring.
Noun: A Kayser-Fleischer ring is a distinctive, pigmented (often golden-brown or greenish) ring that appears at the outer edge of the cornea, which is the clear, front part of the eye. It is a specific and important medical sign, not a symptom experienced by the patient, but an observable finding by a healthcare professional. Its presence is a classic indicator of Wilson's disease, a rare genetic disorder that causes copper to accumulate in the body's tissues.
- The ophthalmologist confirmed the diagnosis after identifying a Kayser-Fleischer ring during the slit-lamp examination.
- The absence of a Kayser-Fleischer ring does not completely rule out Wilson's disease, especially in patients who only show liver symptoms.
- A clear Kayser-Fleischer ring was visible, providing a crucial clue to the underlying metabolic disorder.
- The ring is typically described as being located in the Descemet's membrane of the cornea.
- In medical literature, the finding of a Kayser-Fleischer ring is considered pathognomonic for Wilson's disease in a patient with neurological symptoms, meaning its presence is uniquely characteristic of that disease.
- With effective chelation therapy for Wilson's disease, the Kayser-Fleischer ring may fade or disappear over time.
- Wilson's disease (n): The hereditary disorder characterized by copper accumulation, for which the Kayser-Fleischer ring is a key diagnostic sign.
- Corneal arcus (n): A different, grayish-white ring around the cornea sometimes seen in older adults (arcus senilis) or in individuals with high cholesterol. This is a distinct condition and should not be confused with a Kayser-Fleischer ring.
- Corneal copper deposition: A more descriptive, technical term for the physical phenomenon.
- KF ring: A common medical abbreviation.
- Slit-lamp examination (n): The standard procedure performed by an eye specialist (ophthalmologist) to detect a Kayser-Fleischer ring.
- Hepato-lenticular degeneration: An older, alternative name for Wilson's disease, referencing its effects on the liver () and a part of the brain called the lenticular nucleus.
This term is a proper noun derived from the names of the two physicians, Bernhard Kayser and Bruno Fleischer, who first described the sign. It is always capitalized.
A doctor uses an ophthalmoscope to examine a patient's eye for a Kayser-Fleischer ring.
- a pigmented ring at the outer edge of the cornea of the eye; a symptom of Wilson's disease