macrocytosis

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macrocytosis

A medical technician examines a blood smear showing macrocytosis under a microscope.

Definition
  1. Noun:
    • A medical condition characterized by the presence of macrocytes in the blood: "Macrocytosis" is a laboratory finding indicating that a significant number of red blood cells (erythrocytes) are larger than normal. It is not a disease itself but a sign of an underlying condition.
Usage
  • "Macrocytosis" is a technical term used primarily in medical, clinical, and hematological contexts. It describes an abnormal result in a complete blood count (CBC) test.
  • It is typically used as a singular, uncountable noun (e.g., ).
Examples
  • Noun:
    • The routine blood test revealed mild macrocytosis.
    • Macrocytosis is often associated with vitamin B12 or folate deficiency.
    • The doctor investigated the cause of the persistent macrocytosis.
Advanced Usage
  • "Macrocytosis without anemia": This phrase describes a situation where the red blood cells are enlarged, but the overall red blood cell count and hemoglobin levels are within the normal range.
    • The patient's lab results showed macrocytosis without anemia, which required further evaluation.
Variants and Related Words
  • Macrocyte (n): An abnormally large red blood cell. This is the cell whose presence defines macrocytosis.
    • Under the microscope, the technician observed numerous macrocytes.
  • Macrocytic (adj): Pertaining to or characterized by macrocytes.
    • She was diagnosed with a macrocytic anemia.
Synonyms
  • Macrocythaemia (n): A less common synonym, primarily used in British English.
  • Megalocytosis (n): A near-synonym sometimes used interchangeably, though it can imply more severe enlargement.
Notes on Meaning
  • The core meaning of "macrocytosis" is strictly hematological. It does not have figurative, idiomatic, or non-medical meanings.
  • The condition can be caused by various factors, including nutritional deficiencies (B12, folate), liver disease, hypothyroidism, certain medications, and bone marrow disorders.
macrocytosis

A medical technician examines a blood smear showing macrocytosis under a microscope.

Noun
  1. the presence of macrocytes in the blood

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