monocytic leukaemia
Definition
Noun A type of leukemia (a cancer of the blood-forming tissues) characterized by the abnormal proliferation and accumulation of monocytes and their immature precursors, called monoblasts, in the blood and bone marrow.
Usage
This is a specific medical term used in oncology and hematology. It is typically used in clinical, diagnostic, and research contexts. * The patient's blood smear showed a high count of atypical monocytes, leading to a diagnosis of monocytic leukaemia. * Monocytic leukaemia is one of the subtypes of acute myeloid leukemia (AML).
Advanced Usage
- The term is often part of a more specific classification, such as acute monocytic leukemia (AML-M5 according to the FAB classification system).
- It can be discussed in terms of its cytogenetic or molecular abnormalities, which guide treatment.
Variants and Related Words
- Monocytic leukemia (US English spelling, without the 'ae').
- Monoblastic leukemia: A closely related term sometimes used when the dominant cell is the very immature monoblast.
- Acute Myeloid Leukemia (AML): The broader category of leukemia under which monocytic leukemia is classified.
Synonyms
- Monocyte leukemia
- AML-M5 (FAB classification)
- Acute monocytic/monoblastic leukemia
Note: In medical terminology, synonyms are often precise classifications rather than interchangeable common words.
Noun
-
leukemia characterized by the proliferation of monocytes and monoblasts in the blood
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