Definition

1. Noun:
   • A type of acute myeloid leukemia: "Myeloblastic leukemia" is a specific, aggressive cancer of the blood and bone marrow. It is characterized by the rapid overproduction of immature white blood cells called myeloblasts, which crowd out healthy blood cells.

Usage

• This term is used exclusively in medical and clinical contexts to diagnose and classify a specific form of leukemia. It is a technical term.
• It is often used with determiners like "a case of," "diagnosed with," or "treatment for."

Examples

• Noun:
  • The patient was diagnosed with myeloblastic leukemia after a bone marrow biopsy.
  • Acute myeloblastic leukemia requires prompt and intensive chemotherapy.
  • Research into new therapies for myeloblastic leukemia is ongoing.

Advanced Usage

• The term is frequently modified to specify subtypes, such as "acute myeloblastic leukemia" (AML) or to indicate genetic markers, e.g., "AML with recurrent genetic abnormalities."
• It may be contrasted with other forms of leukemia in medical literature, such as "lymphoblastic leukemia."

Variants and Related Words

• Myeloblast (n): The immature, cancerous cell that defines this disease.
• Acute Myeloid Leukemia (AML) (n): The broader, more commonly used clinical category that includes myeloblastic leukemia.
• Leukemia (n): The general term for cancers of the blood-forming tissues.

Synonyms

• Acute myelogenous leukemia: A synonymous term frequently used in medical contexts.
• AML: The standard acronym for the disease category.

Notes on Meaning

• "Myeloblastic leukemia" is not a general term for cancer or illness; it refers to one precise type of blood cancer.
• The "myeloblastic" component specifies the cell of origin (myeloblasts, which develop into granulocytes), distinguishing it from leukemias arising from lymphocytes (lymphoblastic).

Noun

1. a malignant neoplasm of blood-forming tissues; characterized by numerous myeloblasts in the blood stream