naltrexone

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naltrexone

A doctor prescribes naltrexone to a patient.

Definition

Noun A synthetic drug that acts as an opioid antagonist. It blocks the effects of opioids (such as heroin or morphine) by binding to opioid receptors in the brain without activating them. It is used primarily in the management of alcohol and opioid dependence.

Usage

Naltrexone is used as a medication to support recovery from addiction. * The doctor prescribed naltrexone to help reduce cravings for alcohol. * Treatment for opioid use disorder often includes naltrexone therapy.

Advanced Usage
  • Extended-release injectable naltrexone: A long-acting formulation administered as a monthly injection, which can improve adherence to treatment.
    • The patient received an extended-release naltrexone injection to support their recovery program.
  • Naltrexone implant: A small device surgically placed under the skin that releases the drug over a period of several months.
    • The naltrexone implant provides a continuous dose to prevent relapse.
Variants and Related Words
  • Opioid antagonist: The class of drugs to which naltrexone belongs.
  • Revia®: A common brand name for oral naltrexone.
  • Vivitrol®: The brand name for the extended-release injectable form of naltrexone.
Synonyms
  • Opioid blocker
  • Opioid receptor antagonist
Notes on Meaning

It is critical to distinguish naltrexone from other addiction medications. Unlike methadone or buprenorphine, which are opioid agonists or partial agonists, naltrexone is a pure antagonist with no opioid effects. It is used only after a patient has fully detoxified from opioids to prevent severe withdrawal symptoms.

naltrexone

A doctor prescribes naltrexone to a patient.

Noun
  1. an oral antagonist against the action of opiates