necrosis

/ne'krousis/
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necrosis

A doctor examines a tissue sample showing necrosis under a microscope.

Definition
  1. Noun:
    • The localized death of living cells: A pathological process in biology and medicine where cells in a specific tissue or organ die due to factors like infection, toxins, injury, or the interruption of blood supply. This is not a programmed cell death (apoptosis) but rather a result of external damage.
Usage
  • Necrosis is used as a non-count noun to describe the general process or state of tissue death.
  • Necrosis can be used with a modifier to specify the type or cause (e.g., coagulative necrosis, avascular necrosis).
  • Example:
  • Example:
Advanced Usage
  • "To undergo necrosis": Describes the process where tissue begins to die.
    • Without treatment, the damaged muscle began to undergo necrosis.
  • "Area/Zone of necrosis": Refers to the specific region where cell death has occurred.
    • The scan revealed a large area of necrosis in the liver.
Variants and Related Words
  • Necrotic (adj): Pertaining to or affected by necrosis.
    • The surgeon removed the necrotic tissue from the burn.
  • Necrose (verb, less common): To cause or undergo necrosis.
    • The toxin can necrose the surrounding cells.
Synonyms
  • Cell death: A broader term that includes both necrosis and apoptosis.
  • Gangrene: A type of necrosis often associated with infection and lack of blood flow, typically in a limb.
  • Infarction: Tissue death (necrosis) caused by a lack of blood supply.
Related Phrases and Terms
  • Avascular necrosis: Necrosis due to a loss of blood supply to a bone.
    • Steroid use is a risk factor for avascular necrosis of the hip.
  • Caseous necrosis: A form of necrosis with a cheese-like appearance, often associated with tuberculosis.
    • The biopsy showed caseous necrosis, confirming the diagnosis.
  • Liquefactive necrosis: Necrosis where dead tissue becomes liquefied, common in brain injuries or bacterial infections.
    • The cerebral abscess resulted in liquefactive necrosis.
necrosis

A doctor examines a tissue sample showing necrosis under a microscope.

Noun
  1. the localized death of living cells (as from infection or the interruption of blood supply)