Definition

1. Noun:
   • The localized death of living cells: A pathological process in biology and medicine where cells in a specific tissue or organ die due to factors like infection, toxins, injury, or the interruption of blood supply. This is not a programmed cell death (apoptosis) but rather a result of external damage.

Usage

• Necrosis is used as a non-count noun to describe the general process or state of tissue death.
• Necrosis can be used with a modifier to specify the type or cause (e.g., coagulative necrosis, avascular necrosis).
• Example:
• Example:

Advanced Usage

• "To undergo necrosis": Describes the process where tissue begins to die.
  • Without treatment, the damaged muscle began to undergo necrosis.
• "Area/Zone of necrosis": Refers to the specific region where cell death has occurred.
  • The scan revealed a large area of necrosis in the liver.

Variants and Related Words

• Necrotic (adj): Pertaining to or affected by necrosis.
  • The surgeon removed the necrotic tissue from the burn.
• Necrose (verb, less common): To cause or undergo necrosis.
  • The toxin can necrose the surrounding cells.

Synonyms

• Cell death: A broader term that includes both necrosis and apoptosis.
• Gangrene: A type of necrosis often associated with infection and lack of blood flow, typically in a limb.
• Infarction: Tissue death (necrosis) caused by a lack of blood supply.

Related Phrases and Terms

• Avascular necrosis: Necrosis due to a loss of blood supply to a bone.
  • Steroid use is a risk factor for avascular necrosis of the hip.
• Caseous necrosis: A form of necrosis with a cheese-like appearance, often associated with tuberculosis.
  • The biopsy showed caseous necrosis, confirming the diagnosis.
• Liquefactive necrosis: Necrosis where dead tissue becomes liquefied, common in brain injuries or bacterial infections.
  • The cerebral abscess resulted in liquefactive necrosis.

Noun

1. the localized death of living cells (as from infection or the interruption of blood supply)