Definition

1. Noun:
   • A non-steroidal anti-inflammatory drug (NSAID) formerly used to treat pain and inflammation associated with conditions like arthritis and bursitis. It is a metabolite of phenylbutazone. Note: Due to the risk of serious side effects, its medical use is now very restricted or discontinued in many countries.

Usage

• This word functions exclusively as a noun. It refers specifically to a chemical compound and pharmaceutical substance.
• It is typically used in formal, medical, or scientific contexts (e.g., pharmacology, medical history, clinical discussions).

Examples

• Noun:
  • The physician prescribed oxyphenbutazone for the patient's acute bursitis.
  • Due to its potential toxicity, oxyphenbutazone has been largely withdrawn from the market.
  • The study compared the efficacy of oxyphenbutazone with newer anti-inflammatory agents.

Advanced Usage

• Historical Context: When discussing the history of pharmacology, "oxyphenbutazone" is cited as an example of an older NSAID whose use declined after the discovery of its severe adverse effects, such as bone marrow suppression.
  • In the mid-20th century, oxyphenbutazone was a common treatment for gout before safer alternatives were developed.

Variants and Related Words

• Phenylbutazone (n): The parent drug from which oxyphenbutazone is derived.
• NSAID (n, abbreviation): Non-Steroidal Anti-Inflammatory Drug. This is the broader drug class to which oxyphenbutazone belongs.
• Tandearil (n): A former trade name for oxyphenbutazone.

Synonyms

• Anti-inflammatory agent (n): A general term for a substance that reduces inflammation.
• (Formerly) Tandearil (n): The brand name synonym.

Notes on Meaning

• The primary and only common meaning of "oxyphenbutazone" is as the specific pharmaceutical drug described in the definition. It does not have idiomatic or figurative meanings. Its usage is highly specialized.

Noun

1. an anti-inflammatory drug (trade name Tandearil) used to treat arthritis and bursitis