recombinant human insulin
Noun: A synthetic form of the hormone insulin, produced using recombinant DNA technology. This process involves inserting the human gene for insulin into bacteria or yeast, which then produce insulin that is chemically identical to the insulin naturally produced by the human pancreas. It is used to treat diabetes mellitus.
This term is used in medical, pharmaceutical, and scientific contexts to specify the origin and manufacturing method of the insulin. It distinguishes this type of insulin from older forms derived from animal sources (e.g., bovine or porcine insulin). * The patient was switched to recombinant human insulin due to an allergy to animal-based insulin. * The development of recombinant human insulin was a major breakthrough in biotechnology.
- As a Modifier: The term is often used attributively (like an adjective) before other nouns.
- The recombinant human insulin market has grown significantly.
- They studied the pharmacokinetics of recombinant human insulin formulations.
- Humulin: A well-known trade name for recombinant human insulin.
- Biosynthetic human insulin: A synonymous term emphasizing the biological production method.
- rHI: A common abbreviation used in scientific literature.
- Insulin analog: A related but distinct term for modified forms of insulin (e.g., insulin lispro, insulin glargine) that are also produced via recombinant technology but have altered amino acid sequences to change their properties.
- Biosynthetic human insulin
- Human insulin (in contexts where the recombinant origin is implied or understood)
The core meaning specifies two key aspects: 1. Recombinant: It is produced through genetic engineering. 2. Human: Its amino acid sequence is identical to the insulin hormone produced by humans. It does not refer to insulin analogs (modified versions) or insulin derived from human cadavers (a historical source).
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a form of insulin (trade name Humulin) made from recombinant DNA that is identical to human insulin; used to treat diabetics who are allergic to preparations made from beef or pork insulin
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