siderochrestic anaemia
Noun A type of refractory anemia (a condition where the bone marrow fails to produce enough healthy red blood cells, and which does not respond well to standard treatments) characterized by the presence of abnormal, iron-loaded red blood cell precursors called sideroblasts in the bone marrow.
This is a highly specific medical term. * The patient's blood work and bone marrow biopsy confirmed a diagnosis of siderochrestic anaemia. * Siderochrestic anaemia is distinguished from other anemias by the presence of ringed sideroblasts under microscopic examination.
- The term is often used in hematology (the study of blood) and clinical pathology reports.
- It describes a failure of the bone marrow to properly incorporate iron into hemoglobin within developing red blood cells, leading to iron accumulation inside the cells' mitochondria.
- The spelling "anaemia" is standard in British English; the American English spelling is "anemia" (siderochrestic anemia).
- Sideroblastic anemia (noun): A broader category of anemias characterized by the presence of sideroblasts, which includes siderochrestic anemia as a specific type.
- Refractory anemia (noun): The general class of anemias that are resistant to treatment, under which siderochrestic anemia is classified.
- Sideroblast (noun): The abnormal red blood cell precursor that defines this condition.
- Refractory sideroblastic anemia
- Sideroblastic anaemia (in a general sense)
This term is for academic and medical contexts. It is not used in everyday language. Diagnosis and discussion of this condition should always be conducted by qualified medical professionals.
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refractory anemia characterized by sideroblasts in the bone marrow
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