systemic lupus erythematosus

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systemic lupus erythematosus

A doctor explains the symptoms of systemic lupus erythematosus to a patient.

Definition

Noun: * An autoimmune disease: A chronic inflammatory disease where the body's immune system mistakenly attacks its own healthy tissues and organs, particularly connective tissue. * A multi-system disorder: It can affect many different body systems, including the skin, joints, kidneys, blood cells, brain, heart, and lungs. * Characterized by variable features: Its symptoms are highly variable and may include fatigue, joint pain, skin rashes (often a facial "butterfly" rash), fever, and sensitivity to sunlight.

Usage Examples
  • Noun:
    • The patient was diagnosed with systemic lupus erythematosus after presenting with joint pain and a characteristic facial rash.
    • Managing systemic lupus erythematosus often requires a combination of medication and lifestyle changes.
    • Her systemic lupus erythematosus went into remission, allowing her to resume many of her normal activities.
Advanced Usage
  • "SLE flare" or "lupus flare": A period when the symptoms of systemic lupus erythematosus become significantly more active or severe.
    • Stress can sometimes trigger an SLE flare.
  • In formal medical contexts, the term is often abbreviated to "SLE" after being spelled out once.
    • The study focused on new treatment protocols for SLE.
Variants and Related Words
  • Lupus (n.): A common, informal shorthand for systemic lupus erythematosus. (Note: "Lupus" can also refer to other conditions, like discoid lupus, which primarily affects the skin).
  • Lupus nephritis (n.): A serious complication of systemic lupus erythematosus involving inflammation of the kidneys.
  • Drug-induced lupus (n.): A lupus-like disease caused by certain medications, which usually resolves after the medication is stopped.
Synonyms
  • SLE (the standard medical abbreviation).
  • Lupus (common, but less precise, shorthand).
Related Phrases
  • Butterfly rash: A common red, butterfly-shaped rash across the cheeks and nose, often associated with systemic lupus erythematosus.
    • The presence of a butterfly rash is a key diagnostic clue for systemic lupus erythematosus.
  • Autoimmune disorder/disease: The broader category of conditions to which systemic lupus erythematosus belongs.
    • Systemic lupus erythematosus is one of the most common autoimmune disorders.
systemic lupus erythematosus

A doctor explains the symptoms of systemic lupus erythematosus to a patient.

Noun
  1. an inflammatory disease of connective tissue with variable features including fever and weakness and fatigability and joint pains and skin lesions on the face or neck or arms