tophi

tophi

A patient's hand shows several small tophi near the joints.

Definition
  1. Noun (plural of ):
    • Medical condition: "Tophi" are deposits of urate crystals that form in the body, typically around joints or in soft tissue, as a result of chronic gout. They appear as hard, chalky nodules.
Usage Examples
  • (Urate crystal deposits formed as a complication of gout.)
  • (Medical professionals recognized these nodules as indicators of high uric acid levels.)
Advanced Usage
  • "tophaceous gout": gout characterized by the presence of tophi.

    • Tophaceous gout can lead to joint deformity if untreated. (Gout with urate deposits causing structural damage.)
  • "tophi resolution": the reduction or disappearance of tophi with treatment.

    • Medication aimed at lowering uric acid levels can promote tophi resolution. (Treatment reduces the size of crystal deposits.)
Variants and Related Words
  • Tophus (noun, singular): a single deposit of urate crystals.

    • A single tophus was found near the patient's ankle. (One crystal deposit.)
  • Tophaceous (adjective): relating to or characterized by tophi.

    • The tophaceous swelling was surgically removed. (The nodular growth was excised.)
Synonyms
  • Urate deposit: a general term for a collection of uric acid crystals.
  • Gouty nodule: a nodule associated with gout.
Related Idioms
  • "Gouty tophus": a specific term used in medical literature to describe the nodule.
    • The presence of a gouty tophus confirms the diagnosis of chronic gout. (The nodule is a diagnostic marker.)