type IV allergic reaction
Học thuậtThân thiện
Definition
- Noun:
- A delayed hypersensitivity reaction mediated by cells of the immune system (specifically T-cells), rather than by antibodies. It is an allergic reaction that becomes apparent only hours after contact with the allergen.
Usage
- This term is used in medical and immunological contexts to classify and describe a specific mechanism of allergic response.
- It is often contrasted with immediate hypersensitivity reactions (Type I, II, and III).
Examples
- Noun:
- Poison ivy rash is a classic example of a type IV allergic reaction.
- The positive result for the tuberculin skin test indicates a type IV allergic reaction to the antigens.
- Contact dermatitis from nickel in jewelry is caused by a type IV allergic reaction.
Advanced Usage
- "Delayed-type hypersensitivity (DTH)": This is a synonymous term frequently used in medical literature.
- The immunologist explained that the granuloma formation was due to a delayed-type hypersensitivity response.
Variants and Related Words
- Cell-mediated hypersensitivity: Another technical term for this type of reaction.
- Contact dermatitis: A common clinical manifestation of a type IV allergic reaction.
- Hypersensitivity: The broader category of exaggerated immune responses, of which type IV is one kind.
Synonyms
- Delayed hypersensitivity reaction
- Cell-mediated immune reaction (in this specific allergic context)
- Delayed-type hypersensitivity (DTH)
Related Phrases
- T-cell mediated response: Describes the primary immune cells responsible for this reaction.
- The pathology was consistent with a T-cell mediated response to the drug.
Noun
- an allergic reaction that becomes apparent only hours after contact