Definition

1. Verb (transitive):
   • To cause (a tissue or structure) to develop blood vessels or a vascular system. This is a biological/medical process where vessels form to supply blood.
2. Verb (intransitive):
   • To become vascular; to develop blood vessels or a vascular system.

Usage

• The verb "vascularise" (also spelled "vascularize") describes the process by which blood vessels form within a tissue. It is primarily used in biological, anatomical, and medical contexts.
• As a transitive verb, it means an agent (like the body or a surgical procedure) is causing vessel formation something else.
• As an intransitive verb, it means a tissue or structure undergoes the process of developing vessels .

Examples

• Transitive usage:
  • Surgeons aim to vascularise the graft to ensure its survival. (They cause blood vessels to grow into the graft.)
  • The new bio-ink is designed to help vascularise engineered tissues. (It helps create a network of vessels in the tissues.)
• Intransitive usage:
  • After the injury, the surrounding tissue began to vascularise rapidly. (It started developing its own blood vessels.)
  • For the tumor to grow beyond a few millimeters, it must vascularise. (It must acquire its own blood supply.)

Advanced Usage

• "to become vascularised": This passive construction is very common and emphasizes the state or result of the process.
  • Once the implant becomes vascularised, it integrates fully with the host body.
• In developmental biology, the term describes a key stage in embryogenesis or organ formation.

Variants and Related Words

• Vascularize (verb): The preferred spelling in American English.
• Vascularisation / Vascularization (noun): The process or result of becoming vascular.
  • Angiogenesis is a key mechanism in the vascularisation of tumors.
• Revascularise (verb): To restore blood flow to a tissue, often surgically.
• Avascular (adjective): Lacking blood vessels.
• Vascular (adjective): Relating to or containing blood vessels.

Synonyms

• Angiogenize (less common, more technical): To undergo angiogenesis (the formation of new blood vessels).
• Perfuse (in some contexts, though it emphasizes the flow of fluid through vessels rather than their formation).

Antonyms

• Devascularise (verb): To deprive of blood vessels or blood supply.
• Necrose (verb): To undergo death of tissue, often due to lack of blood supply.

Verb

1. make vascular
   • the yolk sac is gradually vascularized
2. become vascular and have vessels that circulate fluids
   • The egg yolk vascularized