zalcitabine

Thân thiện

A doctor prescribes zalcitabine as part of an HIV treatment plan.

Definition

Noun: - An antiviral drug used to combat HIV infection: Zalcitabine is a synthetic nucleoside analogue that inhibits the replication of human immunodeficiency virus (HIV). It was historically used as part of antiretroviral therapy.

Usage Examples

• Noun:
  • The doctor prescribed zalcitabine in combination with other medications to manage the patient's HIV infection.
  • Due to its side effects, the use of zalcitabine has largely been superseded by newer antiretroviral drugs.

Advanced Usage

• Historical context in treatment: Zalcitabine is often discussed in the context of the evolution of HIV/AIDS therapy, representing an early generation of nucleoside reverse transcriptase inhibitors (NRTIs).
  • Early combination therapies frequently included drugs like zidovudine and zalcitabine.

Variants and Related Words

• ddC (n): Abbreviation for dideoxycytidine, which is the chemical name for zalcitabine.
  • The compound ddC was an important early NRTI.
• Hivid (n): A former brand name under which zalcitabine was marketed.
  • Hivid was withdrawn from the market in the early 2000s.

Synonyms

• Dideoxycytidine: The systematic chemical name for the drug.
• Nucleoside reverse transcriptase inhibitor (NRTI): The class of antiretroviral drugs to which zalcitabine belongs.

Học thuật

Noun

1. an antiviral drug used to combat HIV infection

Từ đồng nghĩa

• dideoxycytosine
• ddC
• DDC