zalcitabine
Definition
Noun: - An antiviral drug used to combat HIV infection: Zalcitabine is a synthetic nucleoside analogue that inhibits the replication of human immunodeficiency virus (HIV). It was historically used as part of antiretroviral therapy.
Usage Examples
- Noun:
- The doctor prescribed zalcitabine in combination with other medications to manage the patient's HIV infection.
- Due to its side effects, the use of zalcitabine has largely been superseded by newer antiretroviral drugs.
Advanced Usage
- Historical context in treatment: Zalcitabine is often discussed in the context of the evolution of HIV/AIDS therapy, representing an early generation of nucleoside reverse transcriptase inhibitors (NRTIs).
- Early combination therapies frequently included drugs like zidovudine and zalcitabine.
Variants and Related Words
- ddC (n): Abbreviation for dideoxycytidine, which is the chemical name for zalcitabine.
- The compound ddC was an important early NRTI.
- Hivid (n): A former brand name under which zalcitabine was marketed.
- Hivid was withdrawn from the market in the early 2000s.
Synonyms
- Dideoxycytidine: The systematic chemical name for the drug.
- Nucleoside reverse transcriptase inhibitor (NRTI): The class of antiretroviral drugs to which zalcitabine belongs.
Noun
-
an antiviral drug used to combat HIV infection
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