Bextra

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Thân thiện
Definition

Proper noun: A brand name for the drug valdecoxib, a nonsteroidal anti-inflammatory drug (NSAID) that is a selective cyclooxygenase-2 (COX-2) inhibitor. It was formerly prescribed to relieve pain and inflammation, particularly for conditions like arthritis and menstrual pain, with the intended benefit of reducing gastrointestinal side effects common to other NSAIDs.

Usage
  • Bextra was withdrawn from the market in 2005 due to safety concerns.
  • The doctor explained that Bextra was designed to be gentler on the stomach than older painkillers.
  • Studies on the cardiovascular risks associated with Bextra led to its removal.
Advanced Usage
  • "Bextra controversy": Refers to the period of scrutiny, legal challenges, and eventual market withdrawal of the drug due to its associated risks of serious skin reactions and cardiovascular events.
    • The Bextra controversy highlighted important issues in pharmaceutical regulation.
Variants and Related Words
  • Valdecoxib (n): The generic, non-branded name for the pharmaceutical compound marketed as Bextra.
  • COX-2 inhibitor (n): The class of drugs to which Bextra (valdecoxib) belongs. Other examples include celecoxib (Celebrex) and rofecoxib (Vioxx, also withdrawn).
Synonyms
  • Valdecoxib (scientific/generic name synonym)
Notes on Meaning

This word is almost exclusively used as a proper noun referring to the specific, now-discontinued, brand-name medication. It is primarily encountered in historical, medical, or legal contexts discussing pharmaceutical history and drug safety. It is not used in general language.

Noun
  1. a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tract

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