Definition

Noun: 1. A pathological condition: A disorder characterized by the abnormal deposition of a waxy, starch-like protein called amyloid in one or more organs or tissues of the body. This buildup can disrupt normal organ function. 2. A secondary condition: It is often a secondary complication of other chronic diseases, such as rheumatoid arthritis, tuberculosis, or multiple myeloma.

Usage Examples

• The patient's kidney failure was ultimately attributed to amyloidosis.
• Diagnosing amyloidosis typically requires a tissue biopsy to confirm the presence of amyloid deposits.
• Treatment for amyloidosis focuses on managing the underlying chronic disease and supporting the function of affected organs.

Advanced Usage

• Systemic amyloidosis: Refers to a form where amyloid deposits are widespread throughout the body, affecting multiple organ systems.
• Localized amyloidosis: Describes a form where amyloid deposits are confined to a single organ or tissue site.

Variants and Related Words

• Amyloid (noun/adjective): The insoluble fibrous protein that accumulates abnormally. Also used to describe something having a starch-like characteristic.
• Amyloidogenic (adjective): Having the propensity to form amyloid. Often used in research contexts.

Synonyms

• Amyloid disease
• Amyloid deposition disease

Notes on Meaning

The core meaning of "amyloidosis" is exclusively medical and pathological. It does not have everyday, figurative, or idiomatic uses. Its meaning is consistently tied to the specific disease process of amyloid protein accumulation.

Noun

1. a disorder characterized by deposit of amyloid in organs or tissues; often secondary to chronic rheumatoid arthritis or tuberculosis or multiple myeloma