antihemophilic globulin
Definition
Noun: - A coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A: Antihemophilic globulin is a specific protein in blood plasma that is essential for the normal clotting of blood. It is also known medically as Factor VIII. A deficiency or absence of this factor causes the bleeding disorder hemophilia A.
Usage
- This term is used in medical and scientific contexts to refer to the specific blood-clotting protein, Factor VIII.
- It is often discussed in relation to the diagnosis, treatment, and pathology of coagulation disorders.
Examples
- The patient's bleeding disorder was diagnosed as a severe deficiency of antihemophilic globulin.
- Treatment for classic hemophilia involves intravenous infusion of concentrated antihemophilic globulin.
- The laboratory test measures the activity level of antihemophilic globulin in the blood plasma.
Advanced Usage
- Therapeutic Use: The term is central when discussing replacement therapy for hemophilia A patients.
- The development of recombinant antihemophilic globulin has improved the safety of treatment.
Variants and Related Words
- Factor VIII: The standard medical and scientific synonym for antihemophilic globulin.
- Coagulation factor: The general category of proteins to which antihemophilic globulin belongs.
- Hemofil: A specific brand name for a therapeutic preparation of this factor.
Synonyms
- Factor VIII: The most common direct synonym in medical terminology.
- Antihemophilic factor (AHF): Another formal name for the same substance.
Related Phrases
- Antihemophilic globulin concentrate: Refers to the medicinal product derived from blood plasma or made recombinantly, used for treatment.
- The hospital stocked antihemophilic globulin concentrate for emergency surgeries.
Noun
-
a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A
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