azt
Học thuậtThân thiện
Definition
Noun: - An antiviral drug used in the treatment of AIDS: AZT is the common name for the medication zidovudine, which was one of the first drugs approved to fight the Human Immunodeficiency Virus (HIV). It works by inhibiting the virus's ability to replicate.
Usage
- AZT is typically prescribed as part of a combination therapy for HIV/AIDS.
- It is known by its trade name, Retrovir.
- The use of AZT marked a significant advancement in the management of HIV infection.
Examples
- Noun:
- The doctor added AZT to the patient's treatment regimen.
- Early trials showed that AZT could slow the progression of the disease.
Advanced Usage
- "AZT resistance": Refers to when the HIV virus mutates and becomes less susceptible to the effects of AZT, reducing the drug's effectiveness.
- The development of AZT resistance is a major challenge in long-term HIV management.
Variants and Related Words
- Zidovudine (n): The generic, scientific name for AZT.
- Retrovir (n): A primary trade name for the drug AZT.
- NRTI (Nucleoside Reverse Transcriptase Inhibitor) (n): The class of antiretroviral drugs to which AZT belongs.
Synonyms
- Zidovudine
- Retrovir (trade name)
Notes on Meaning
AZT specifically refers to this one pharmaceutical compound. It is not a general term for AIDS medication but denotes this historically significant first-generation drug. Its introduction transformed AIDS from a rapidly fatal diagnosis into a more manageable chronic condition, though with notable side effects.
Noun
- an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow