barbituric acid
Definition
Noun: 1. A white crystalline organic compound: A white, odorless, crystalline acid with the chemical formula C₄H₄N₂O₃, derived from pyrimidine. It is the parent structure of a large class of sedative and hypnotic drugs known as barbiturates.
Usage
- As a chemical precursor: The primary use of barbituric acid is as the fundamental chemical building block for synthesizing barbiturate drugs.
- In pharmaceutical chemistry: Barbituric acid itself has no central nervous system activity, but its derivatives are crucial in medicinal chemistry.
Examples
- Noun:
- The laboratory synthesized barbituric acid for research into new sedative compounds.
- Barbituric acid is a key intermediate in the manufacture of many pharmaceutical products.
Advanced Usage
- "Malonylurea": This is an alternative chemical name for barbituric acid, referring to its structure derived from malonic acid and urea.
- The compound, known chemically as malonylurea or barbituric acid, was first created in 1864.
Variants and Related Words
- Barbiturate (noun): Any of a class of drugs derived from barbituric acid, acting as central nervous system depressants.
- Phenobarbital is a well-known barbiturate used to treat seizures.
Synonyms
- Malonylurea: The systematic chemical name.
- Pyrimidinetrione: A name describing its chemical structure as a pyrimidine ring with three ketone groups.
Noun
-
a white crystalline acid derived from pyrimidine; used in preparing barbiturate drugs
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