Definition

Noun: The physiological process by which liquid blood transforms into a semisolid gel, forming a blood clot. This is a vital mechanism to prevent excessive bleeding (hemorrhage) following an injury to a blood vessel.

Usage

The term "blood coagulation" is used to describe the complex, multi-step biological cascade that results in clot formation. - The doctor explained that the medication would slow down his blood coagulation to prevent dangerous clots. - A deficiency in certain vitamins can impair normal blood coagulation. - Researchers are studying the intricate proteins involved in the cascade of blood coagulation.

Advanced Usage

• "to initiate/trigger blood coagulation": Refers to the start of the clotting process, often due to vascular injury.
  • Exposure of tissue factor at the injury site is a primary event that triggers blood coagulation.
• "a disorder of blood coagulation": Describes a medical condition where the clotting process is abnormal.
  • Hemophilia is a well-known inherited disorder of blood coagulation.

Variants and Related Words

• Coagulation (n): The general process of a liquid changing to a solid or semisolid state. "Blood coagulation" is a specific type of coagulation.
• Clotting (n): A common synonym for coagulation, especially in the context of blood. Often used in the phrase "blood clotting."
• Hemostasis (n): The broader physiological process of stopping bleeding, which includes vascular constriction, platelet plug formation, and blood coagulation.
• Coagulate (v): The verb form meaning to change from a fluid into a thickened mass.
  • The blood began to coagulate at the wound site.

Synonyms

• Blood clotting
• Clot formation

Related Phrases

• Coagulation cascade: The specific series of sequential reactions involving clotting factors that lead to fibrin formation.
  • Factor VIII is a crucial protein in the intrinsic pathway of the coagulation cascade.
• Coagulation factors: The plasma proteins (numbered I through XIII) that are essential for blood coagulation.
  • The liver synthesizes most of the coagulation factors.

Noun

1. a process in which liquid blood is changed into a semisolid mass (a blood clot)