counterstain

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counterstain

The technician applies a counterstain to the tissue sample.

Definition
  1. Noun:
    • A stain of a contrasting color used in microscopy or histology to make certain structures visible when the primary stain does not show them clearly. It provides a background or highlights different cellular components.
Usage
  • Noun:
    • The biologist applied a counterstain to the tissue sample to differentiate the nucleus from the cytoplasm.
    • Safranin is commonly used as a counterstain in the Gram staining procedure to color Gram-negative bacteria pink.
Advanced Usage
  • In a technical context: The term is primarily used in scientific disciplines like biology, histology, and pathology.
    • After the primary stain, a counterstain was applied to provide contrast and enhance the visualization of specific organelles.
Variants and Related Words
  • Counterstaining (gerund/noun): The process or technique of applying a counterstain.
    • Counterstaining is a critical step in many histological protocols.
  • Counterstained (adjective/verb, past participle): Describes a sample that has been treated with a counterstain.
    • The counterstained slide was ready for examination under the microscope.
Synonyms
  • Secondary stain: A stain applied after the primary stain.
  • Contrast stain: A stain used to provide a contrasting color.
Related Phrases/Idioms

(This term is highly technical and does not have common idiomatic or phrasal verb uses.)

counterstain

The technician applies a counterstain to the tissue sample.

Noun
  1. a stain of contrasting color that is used when the principal stain does not show the structure clearly