de-iodinase

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de-iodinase

The enzyme de-iodinase is active in thyroid hormone regulation.

Definition
  1. Noun:
    • An enzyme that removes the iodine radical: De-iodinase is a specific type of enzyme responsible for catalyzing the removal of iodine atoms from molecules, particularly from thyroid hormones.
Usage
  • Noun:
    • De-iodinase activity is crucial for regulating thyroid hormone levels in the body.
    • Researchers are studying the function of de-iodinase in metabolic processes.
Examples
  • Noun:
    • The de-iodinase enzyme converts the hormone T4 into the more active T3.
    • A deficiency in de-iodinase can lead to hormonal imbalances.
Advanced Usage
  • "De-iodinase pathway": Refers to the biochemical route involving de-iodinase enzymes.

    • The de-iodinase pathway is a key mechanism for local thyroid hormone activation in tissues.
  • "De-iodinase inhibition": The act of blocking or reducing the activity of this enzyme.

    • Certain environmental toxins can cause de-iodinase inhibition.
Variants and Related Words
  • Deiodinase (n): An alternative spelling for de-iodinase.

    • Deiodinase is often used interchangeably with de-iodinase in scientific literature.
  • Deiodination (n): The chemical process of removing iodine, which is catalyzed by de-iodinase.

    • Deiodination of thyroid hormones occurs primarily in the liver and kidneys.
Synonyms
  • Iodothyronine deiodinase: The full technical name for the enzyme.
  • Thyroid hormone deiodinase: A descriptive synonym emphasizing its role with thyroid hormones.
Related Terms
  • Enzyme (n): A protein that acts as a catalyst in biochemical reactions.
  • Thyroid hormone (n): Hormones like T3 and T4 whose metabolism involves de-iodinase.
de-iodinase

The enzyme de-iodinase is active in thyroid hormone regulation.

Noun
  1. an enzyme that removes the iodine radical