erythroblast
Definition
Noun: A nucleated cell found in bone marrow that is a precursor to red blood cells (erythrocytes). It is an immature cell that undergoes several stages of development, losing its nucleus before maturing into a functional red blood cell.
Usage
This is a specialized biological and medical term. It is used to describe a specific stage in hematopoiesis (the formation of blood cells). * The bone marrow biopsy showed an increased number of erythroblasts. * The erythroblast is the last nucleated stage before the cell becomes a reticulocyte.
Advanced Usage
- Normoblast: A more mature, terminally differentiated stage of an erythroblast. The terms are sometimes used interchangeably, though "normoblast" often refers to the stage just before the nucleus is expelled.
- The normoblast eventually extrudes its nucleus to become a reticulocyte.
- Erythroblastosis fetalis: A serious blood disorder in a fetus or newborn infant, often due to Rh incompatibility with the mother, characterized by the presence of erythroblasts in the circulating blood.
- The condition erythroblastosis fetalis requires immediate medical treatment.
Variants and Related Words
- Erythroblastic (adjective): Pertaining to or resembling an erythroblast.
- The patient exhibited an erythroblastic response to the anemia.
- Proerythroblast (noun): An earlier, less mature precursor cell that develops into an erythroblast.
- Erythropoiesis (noun): The process of producing red blood cells.
Synonyms
- Normoblast (in specific contexts)
- Red blood cell precursor
- Immature erythrocyte
Different Meanings
This term has a single, specific meaning in biology and medicine. It does not have common idiomatic or figurative uses.
Noun
-
a nucleated cell in bone marrow from which red blood cells develop
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